Fibroblasts and Mesenchymal Stromal/Stem Cells Are Phenotypically Indistinguishable
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چکیده
منابع مشابه
Salivary Gland NK Cells Are Phenotypically and Functionally Unique
Natural killer (NK) cells and CD8(+) T cells play vital roles in containing and eliminating systemic cytomegalovirus (CMV). However, CMV has a tropism for the salivary gland acinar epithelial cells and persists in this organ for several weeks after primary infection. Here we characterize a distinct NK cell population that resides in the salivary gland, uncommon to any described to date, express...
متن کاملCancer-Associated Fibroblasts in a Human HEp-2 Established Laryngeal Xenografted Tumor Are Not Derived from Cancer Cells through Epithelial-Mesenchymal Transition, Phenotypically Activated but Karyotypically Normal
Cancer-associated fibroblasts (CAFs) play a crucial role in cancer progression and even initiation. However, the origins of CAFs in various cancer types remain controversial, and one of the important hypothesized origins is through epithelial-mesenchymal transition (EMT) from cancer cells. In this study, we investigated whether the HEp-2 laryngeal cancer cells are able to generate CAFs via EMT ...
متن کاملCorrection: Cancer-Associated Fibroblasts in a Human HEp-2 Established Laryngeal Xenografted Tumor Are Not Derived from Cancer Cells through Epithelial-Mesenchymal Transition, Phenotypically Activated but Karyotypically Normal
Copyright: © 2015 Wang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Mesenchymal stem cells are adherent stromal cells, initially isolated from the bone marrow, characterized by their ability to differentiate into mesenchymal tissues such as bone, cartilage and fat. They have also been shown to suppress immune responses in vitro. Because of these properties, mesenchymal stem cells have recently received a very high profile. Despite the dramatic benefits reported...
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Background Vitamin A-storing hepatic stellate cells (HSC) are mainly known for their contribution to fibrogenesis in chronic liver disease, but their identity and function in normal liver remained unclear. Since HSC possess stem/ progenitor cell characteristics [1] their contribution to stem cell-associated functions in the liver was investigated. Stem cell functions in the liver were reported ...
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ژورنال
عنوان ژورنال: Acta Haematologica
سال: 2016
ISSN: 0001-5792,1421-9662
DOI: 10.1159/000445096